Crucial Role Zero Growth Diesels Gene for Children Discovered by Scientists

A gene plays an important role, zero growth in children, as well as zero period of puberty, suggests a study published on Wednesday (3), which, furthermore, shows that it likes people with a mutation in this gene suffer from delays in their development.

Published in the scientific journal Character by a team of British scientists, u evaluates a paper on a study protein, known as MC3L, which acts on the way in which u brain reacts to a hormone, melanocortin.

This hormone is a primary responsible for the pigmentation of a skin. However, in recent years, it has been given other functions, particularly in regulating the performance of appetite. We know that another receptor, called MC4Ur, can favor obesity when it malfunctions due to a genetic anomaly.

On the other hand, zero learned knew the precise role that the MC protein33 rd there’s r plays electronic, by extension, a gene that encodes it in humans, even after some studies in mice suggested that it had some influence of zero growth l.

In synthesis, “humans in what the signaling of a deficient MC3L grows more slowly,” say the authors study perform.

The researchers first looked at a few thousand on British patients who had a zero gene mutation. For this, they used a huge biological database from United kingdom Biobank, an organization that has been compiling this type of information for several years in the United Kingdom, and also electronic data collected by a prospective study carried out decades ago by the University of Bristol.

After several comparisons with groups on individuals in which the ze gene is normally expressed, the scientists established that these mutations were associated with electronic late puberty with slower growth during childhood.

)”We describe a new clinical syndrome linked to a deficiency in MC3Ur”, concluded the authors, who see these results as a clue to address the problems of zero developmental delay in adolescents.

“Our data suggest that agonists on MC33rd there’s r”, ie treatments that stimulate the action of this protein, “could be useful in certain patients with late puberty electronic/or short stature”, the scientists explained. s.

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