More than four million people in over 20 countries take part in this global phenomenon to raise much-needed funds for saving lives.
Several hundred locals participated in last year's event at the Cleveland High School track and drew in $79,000 in donations.
Plans to reach $80,000 in 2013 are already underway.
This year’s theme is Rock ‘n Roll Relay — Rockin’ for a Cure and Rollin’ out Cancer.
A Bolivar County Relay For Life team and committee meeting will be at the Cleveland School District office at 5:15 p.m. on Thursday.
"Anyone with a team or anyone interested in forming a team needs to be there," said event co-chair Nancy Nassar. "We will go over details and discuss the different things people will be doing for fundraisers."
Meetings will continue on a monthly basis until the main event takes place June 7 at the CHS track.
Teams typically average 10 members, but there is no rule against having more or less.
"We just ask that every team member raise at least $100 in order to get a T-shirt," said Nassar.
Some teams hold special events prior to the big affair to help build their fundraising totals.
The Morrison Chapel Baptist Church team will be organizing a 5k walk/run on April 13 to boost team funds. Those interested in registering for the event should contact Nassar at 662-719-1210.
Even those not intending to join a team are encouraged to attend the official relay in June.
"We want to stress that this is a community event," said Nassar. "Even if someone is not on a team they can support the cause by buying a hamburger or hot dog or walking around the track.
"Everyone is affected by cancer. Relay For Life is a great way to show your support. We are confident we'll reach our goal this year."
Nassar said some new activities will be added to the schedule in 2013, but they are being kept secret for the meantime.
The typical format of Relay is summarized as an organized, overnight community fundraising walk.
Teams take turns walking around the track, while food, games and entertainment build camaraderie during the event.
The atmosphere is family-friendly for the entire community.
To learn more about Bolivar County Relay For Life, visit the Facebook page at www.facebook.com/AmericanCancerSocietyRelayForLifeClevelandMs.
Learn more about the organization behind the movement at www.relayforlife.org.