The weekend's festivities will begin on Friday and conclude on May 27.
Starting from 7-9 p.m. on Friday, there will be a meet and greet at the Second Baptist Church Fellowship Hall.
"This is a great time to come fellowship and get reacquainted with former residents of Duncan," said Louise Beasley, program director for the reunion.
Then on Saturday, the celebration will continue with a picnic uptown beginning at 10 a.m. and lasting until dark.
"At 2 p.m. on Saturday, there will be a parade with floats, tractors, the fire department and decorated cars," Beasley added. "Also in the afternoon, we will have gospel and blues performers. Booths will be selling hotdogs and other food items on Main Street across from the town hall."
According to Beasley, this year's event is the seventh reunion the town has had. She explained the town holds the reunion every two years.
A program at Brooks Elementary School on May 27 will wrap up the weekend's festivities for the town.
"On Sunday at 9 a.m., there will be a church service and program. We will have someone give a speech and then there will be a presentation of pictures from the last reunion," she continued. "We will also present awards to individuals who have helped with the reunion in past years."
As for the turnout for the event, Beasley was optimistic, "I expect over 200 people to come out and celebrate. Every year it gets bigger and bigger."
There is no fee to participate during the weekend.
Beasley mentioned a raffle would take place that weekend.
"We will have a raffle for $100 worth of gas. The raffle tickets are $1 each," she said.
Also, T-shirts will be available for purchase all three days of the reunion.
"The prices for the T-shirts differ depending on the size. Baby sizes to adult XL are $10, XXLs are $11, XXXLs are $12 and XXXXLs are $13," she said.